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3d insight pancreatic islet microtissues  (Insphero Inc)

 
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    Structured Review

    Insphero Inc 3d insight pancreatic islet microtissues
    3d Insight Pancreatic Islet Microtissues, supplied by Insphero Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/3d+insight%E2%84%A2+pancreatic+islet+microtissues/islet+microtissues/pmc06697881-181-2-8
    Average 90 stars, based on 1 article reviews
    3d insight pancreatic islet microtissues - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Produced:

    Article Title: Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma
    Article Snippet: Human and rodent 3D InSightTM pancreatic islet microtissues (InSphero AG) were produced from reconstituted dispersed human or rat pancreatic islet cells in a modified manner as described previously ( ) retaining the composition of α, β and δ cells representative of normal endocrine pancreatic islets.

    Modification:

    Article Title: Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma
    Article Snippet: Human and rodent 3D InSightTM pancreatic islet microtissues (InSphero AG) were produced from reconstituted dispersed human or rat pancreatic islet cells in a modified manner as described previously ( ) retaining the composition of α, β and δ cells representative of normal endocrine pancreatic islets.

    Isolation:

    Article Title: Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma
    Article Snippet: Human and rodent 3D InSightTM pancreatic islet microtissues (InSphero AG) were produced from reconstituted dispersed human or rat pancreatic islet cells in a modified manner as described previously ( ) retaining the composition of α, β and δ cells representative of normal endocrine pancreatic islets.

    Incubation:

    Article Title: Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma
    Article Snippet: Human and rodent 3D InSightTM pancreatic islet microtissues (InSphero AG) were produced from reconstituted dispersed human or rat pancreatic islet cells in a modified manner as described previously ( ) retaining the composition of α, β and δ cells representative of normal endocrine pancreatic islets.

    Enzyme-linked Immunosorbent Assay:

    Article Title: Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma
    Article Snippet: Human and rodent 3D InSightTM pancreatic islet microtissues (InSphero AG) were produced from reconstituted dispersed human or rat pancreatic islet cells in a modified manner as described previously ( ) retaining the composition of α, β and δ cells representative of normal endocrine pancreatic islets.

    Quantitative RT-PCR:

    Article Title: Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma
    Article Snippet: Human and rodent 3D InSightTM pancreatic islet microtissues (InSphero AG) were produced from reconstituted dispersed human or rat pancreatic islet cells in a modified manner as described previously ( ) retaining the composition of α, β and δ cells representative of normal endocrine pancreatic islets.



    Similar Products

    3d insight pancreatic islet microtissues  (Insphero Inc)
    90
    Insphero Inc 3d insight pancreatic islet microtissues
    3d Insight Pancreatic Islet Microtissues, supplied by Insphero Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/3d+insight%E2%84%A2+pancreatic+islet+microtissues/islet+microtissues/pmc06697881-181-2-8
    Average 90 stars, based on 1 article reviews
    3d insight pancreatic islet microtissues - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier
    3d insight™ pancreatic islet microtissues  (Insphero Inc)
    90
    Insphero Inc 3d insight™ pancreatic islet microtissues
    Rat pancreatic islets were isolated, dissociated into single cells, replated in microtiter wells (1000 cells/drop), and allowed to form <t>3D</t> <t>microtissues</t> of ~120 μM in diameter over 7 days using inSphero™ technology. Microtissues (n=5 per treatment) were then incubated for 7 days in the absence or presence of compound 18 at the indicated concentrations, and then ( A ) analyzed for cell viability by ATP levels; or ( B ) challenged with glucose (16.7 mM) for 1 hr and analyzed for insulin secretion by ELISA.
    3d Insight™ Pancreatic Islet Microtissues, supplied by Insphero Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/3d+insight%E2%84%A2+pancreatic+islet+microtissues/islet+microtissues/bio_rxiv__495242-167-2-8
    Average 90 stars, based on 1 article reviews
    3d insight™ pancreatic islet microtissues - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Rat pancreatic islets were isolated, dissociated into single cells, replated in microtiter wells (1000 cells/drop), and allowed to form 3D microtissues of ~120 μM in diameter over 7 days using inSphero™ technology. Microtissues (n=5 per treatment) were then incubated for 7 days in the absence or presence of compound 18 at the indicated concentrations, and then ( A ) analyzed for cell viability by ATP levels; or ( B ) challenged with glucose (16.7 mM) for 1 hr and analyzed for insulin secretion by ELISA.

    Journal: bioRxiv

    Article Title: Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma

    doi: 10.1101/495242

    Figure Lengend Snippet: Rat pancreatic islets were isolated, dissociated into single cells, replated in microtiter wells (1000 cells/drop), and allowed to form 3D microtissues of ~120 μM in diameter over 7 days using inSphero™ technology. Microtissues (n=5 per treatment) were then incubated for 7 days in the absence or presence of compound 18 at the indicated concentrations, and then ( A ) analyzed for cell viability by ATP levels; or ( B ) challenged with glucose (16.7 mM) for 1 hr and analyzed for insulin secretion by ELISA.

    Article Snippet: Human and rodent 3D InSight™ pancreatic islet microtissues (InSphero AG) were produced from reconstituted dispersed human or rat pancreatic islet cells in a modified manner as described previously ( ) retaining the composition of α, β and δ cells representative of normal endocrine pancreatic islets.

    Techniques: Isolation, Incubation, Enzyme-linked Immunosorbent Assay

    ( A-C ) Human pancreatic islets were isolated, dissociated into single cells, replated in microtiter wells (1000 cells/drop), and allowed to form 3D microtissues of ~120 μΜ in diameter over 7 days using inSphero™ technology. Microtissues (n=5 per treatment) were then ( A ) treated for 24 hr with tunicamycin (5 μg/ml) in the absence or presence of compound 18 at the indicated concentrations, lysed, and then analyzed for XBP1s/(XBP1s+XBP1u) mRNA levels by RT-QPCR; or ( B and C ) incubated for 7 days in the absence or presence of 18 at the indicated concentrations, and then ( B ) analyzed for cell viability by CellTiterGlo™ assay; or ( C ) challenged with glucose (16.7 mM) for 1 hr and analyzed for insulin secretion by ELISA.

    Journal: bioRxiv

    Article Title: Disruption of IRE1α through its Kinase Domain Attenuates Multiple Myeloma

    doi: 10.1101/495242

    Figure Lengend Snippet: ( A-C ) Human pancreatic islets were isolated, dissociated into single cells, replated in microtiter wells (1000 cells/drop), and allowed to form 3D microtissues of ~120 μΜ in diameter over 7 days using inSphero™ technology. Microtissues (n=5 per treatment) were then ( A ) treated for 24 hr with tunicamycin (5 μg/ml) in the absence or presence of compound 18 at the indicated concentrations, lysed, and then analyzed for XBP1s/(XBP1s+XBP1u) mRNA levels by RT-QPCR; or ( B and C ) incubated for 7 days in the absence or presence of 18 at the indicated concentrations, and then ( B ) analyzed for cell viability by CellTiterGlo™ assay; or ( C ) challenged with glucose (16.7 mM) for 1 hr and analyzed for insulin secretion by ELISA.

    Article Snippet: Human and rodent 3D InSight™ pancreatic islet microtissues (InSphero AG) were produced from reconstituted dispersed human or rat pancreatic islet cells in a modified manner as described previously ( ) retaining the composition of α, β and δ cells representative of normal endocrine pancreatic islets.

    Techniques: Isolation, Quantitative RT-PCR, Incubation, Enzyme-linked Immunosorbent Assay